The Effect of Astrocytic S100B Protein on Memory Conolidation Rats
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چکیده
همدقم : نیئتورپ S100B ورون طابترا لرتنک رد و دوش یم دازآ اه تیسورتسآ زا هک تسا ینیئتورپ ، لگ ی یلا دراد شـقن یسپانیس يریذپ لکش و هظفاح رد لاامتحا و . هـعلاطم ادروخرب یصاخ تیمها زا نورون و تیسورتسآ لولس ود يدرکلمع طابترا تسا ر . ياـه شوـم رد يریگداـی يور رـب پـماکوپیه نورد هـب نیئتورـپ نیا قیرزت رثا رضاح هعلاطم رد تفرگ رارق یسررب دروم ییارحص . شور اه : زا قیقحت نیا رد 40 دش هدافتسا رن ییارحص شوم . يراذگ لوناک و یحارج زا سپ تاناویح هـفرط ود هـیحان رد CA1 زـین و پـماکوپیه 7 ت ، يرواـکیر زور تـح دنتفرگ رارق لاعفریغ يزارتحا يریگدای ) 5 / 0 رپمآ یلیم , 100 زتره , 5 هیناث .( ،شزومآ زا سپ هلصافلاب 5 / 0 نیئتورپ رتیلورکیم S100B , هفرطود تروص هب , فـلتخم ياـهزود رد ) 5 و 50 و 500 و 5000 مرگونان ( هورگ هب دش قیرزت لرتنک هورگ هب نیلاس و یشیامزآ ياه . صخاش ی ياه نامز لک و وکس زا ندمآ نییاپ رد ریخات نیلوا لماش هظفاح و يریگدا ، وکس يور رب هدش يرپس 24 دش شجنس دعب تعاس . هتفای اه : قیرزت 5 مرگونان S100B وکـس زا ندـمآ نییاـپ رد ریخاـت نیلوا صخاش رد ار يراد ینعم شیازفا ، ) 01 / 0 < P ( وکـس يور رـب هدـش يرپـس ناـمز لـک زـین و ) 001 / 0 < P ( ياهزود يروآ تفگش روطب و داد ناشن 500 و 5000 دـنداد ناشن رکذلا قوف صخاش ود ره رد ار يراد ینعم شهاک لرتنک هورگ اب هسیاقمرد ،نیئتورپ نیا مرگونان ) 001 / 0 < P ( . هجیتن يریگ : جیاتن یتیسورتسآ نیئتورپ دهد یم ناشن ام S100B ،دراد هظفاح يور رب یلیدعت تا رثا ، ياـهزود رد هـکیلاح رد ،لیهـست ار هظفاح مرگونان ياه زود رد هکیروطب دنک یم بیرخت ار لاعف ریغ يزارتحا هظفاح مرگورکیم .
منابع مشابه
The Effect of Astrocytic S100B Protein on Memory Conolidation Rats
Introduction: S100B is a protein released from astrocytes, which controls neuroglial relationship and probably plays a role in memory and synaptic plasticity. Study of the functional relationship between astrocytes and neurons is of great importance. The present study was conducted to evaluate the effect of S100B infusion into the CA1 region of the hippocampus, on memory performance in male ...
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